It is all too clear that Lesch-Nyhan Syndrome affects the kidneys. 

Allopurinol is used to assist with heightened uric acid levels. Some doctors claim that an alkalining medicine such as Bi-Cytra may also help the urine to lower acidity levels in the kidneys. The range of opinions regarding treatment is quite extensive and it is always personal according to each patient. 

 Dr. Cooper at University of Iowa who has treated multiple LNS patients. He can be emailed